The gut-brain axis is a bidirectional network between the brain (central nervous system) and the gastrointestinal system (enteric nervous system), with complex components involved such as the vagus nerve, immune factors, neuroendocrine pathways, and microbial metabolites [1].
One of the communication lines between the brain and the gut that coordinates the stress body response is called the 'HPA axis' (hypothalamic pituitary adrenal axis). Both clinical and experimental research suggests that the gut microbiome plays an important role on this communication axis and can indirectly influence our mental health too.
Literature exploring the relationship between the intestinal microbiome and its effects on health and well-being has grown significantly in recent years, and our knowledge of this subject continues to grow [2]. In fact, the number of publications related to the gut-brain axis and the relationship with the gut microbiome has been exploding over the last decade.
Understanding better the communication line between the gut and our brain, makes the gut microbiome a new target for potential new ways to deal with stress and mental balance, potential applications of discoveries are very broad and we're only at the beginning of the possibilities!
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Sophie Cochez
Sophie is a biologist with a master’s degree in medical biology and additional training in microbiome science. Passionate about translating scientific knowledge into meaningful solutions, she co-founded Biodami to develop innovative, evidence-based supplements that support the microbiome and empower people to feel their best.
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References: 1. Sandhu KV, Sherwin E, Schellekens H, Stanton C, Dinan TG, Cryan JF. Feeding the microbiota-gut-brain axis: diet, microbiome, and neuropsychiatry. Transl Res. 2017 Jan;179:223-244. doi: 10.1016/j.trsl.2016.10.002. Epub 2016 Oct 21. PMID: 27832936. |
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